These newly discovered cells, named EndoMac progenitors, were found in the outer layer of aortas in adult mice. While the existence of such cells has been theorized for over a century, this marks the first time they have been identified. The discovery is the culmination of nine years of research.
The researchers found that EndoMac progenitors are activated in response to injury or poor blood flow, rapidly expanding to aid in the healing process, as reported by Xinhua news agency. Ongoing studies suggest these cells could significantly enhance healing in conditions like diabetes, where the body struggles with tissue repair.
“When we transplanted these progenitors into diabetic wounds, we observed a dramatic improvement in healing within days,” said Sanuri Liyange, a member of the research team, in a media statement.
Liyange described the discovery as a potential game-changer for patients suffering from chronic wounds. The team is hopeful that this breakthrough will lead to more effective treatments that enhance the body’s natural healing processes and support long-term tissue maintenance.